pepteed
Research5 min readUpdated May 2026

GHK-Cu: the copper peptide, explained

GHK-Cu — copper tripeptide-1 — is one of the most recognised peptides in cosmetic and cellular research. This primer covers what it is structurally and how it is handled, written for an in-vitro research audience with no therapeutic or dosing claims.

What it is

GHK is a tripeptide made of glycine, histidine and lysine. On its own it is GHK; complexed with a copper(II) ion it becomes GHK-Cu. The copper ion is integral to the molecule's identity, which is why the complex is named separately from the bare tripeptide.

Why it is studied

GHK-Cu appears widely in skin-model and cellular research, and is a common ingredient reference point in the cosmetic literature. Any findings belong to the studies themselves — this page makes no claim about effects in humans.

Handling notes

  • Supplied lyophilised, often with a characteristic blue tint from the copper complex.
  • Reconstitute gently; keep the dry solid sealed, cold and dark.
  • Refrigerate after reconstitution and protect from prolonged light exposure.

For in-vitro research use only. Not for human or veterinary use.

Mentioned in the catalog
For in-vitro research use only. This guide covers general laboratory handling and is not medical, clinical or dosing advice.